Human African trypanosomiasis of the CNS: current issues and challenges.
نویسنده
چکیده
Human African trypanosomiasis (HAT), also known as sleeping sickness, is a major cause of mortality and morbidity in sub-Saharan Africa. Current therapy with melarsoprol for CNS HAT has unacceptable side-effects with an overall mortality of 5%. This review discusses the issues of diagnosis and staging of CNS disease, its neuropathogenesis, and the possibility of new therapies for treating late-stage disease.
منابع مشابه
Difficulties in Diagnostic Staging of Human African Trypanosomiasis
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عنوان ژورنال:
- The Journal of clinical investigation
دوره 113 4 شماره
صفحات -
تاریخ انتشار 2004